Safety – University of Copenhagen


Safe use of plant extracts


Eclipta alba:

 No health risk to humans for using an extract of this plant for seed treatment was found.

Aqueous extract from the plants is currently used in traditional Burkinabe, Indian and Chinese medicin.

Review by Jahan et al 2014: Ethnopharmacological significance of Eclipta alba (L.) Hassk. (Asteracea). International Scholarly Research Notices, 2014, 385969.


In the present project extract from dried leaves and aqueous extract of whole plants (roots, stem and leaves) were tested for toxicity according to OECD protocols of acute toxicity following the animals (rabbits and rats) every day up to 14 days after exposure to the extract.


OECD guideline test 423 (Toxicity when eaten)

OECD guideline test 404 (Toxicity to the skin)

OECD guideline test 405 (Toxicity to the eye)

Testing was carried out by accredited laboratory M/s Vipragen Biosciences Private Limited, Mysore, India.

  • Leaves

No toxicity of the extract was found

Publication Udayashankar et al., 2015.

  • Whole plant

No toxicity of the extract was found.

Report conclusions 2018


Balanites aegyptiaca


The extract from bark (Protocol-3) was not tested for toxicity in the present project.

A previous study did not find indications of acute toxicity in rabbits:

Mohamed et al 1999: Some pharmacological and toxicological studies on Balanites aegyptiaca bark

Phytotherapy Research, Volume13, Issue5, Pages 439-441